Mechanism of a Friedel-Crafts Alkylation (BioChem) and its role in combating illness
Firstly, the Friedel-Crafts Alkylation reaction synthesizes alkylated products, such as: alkylbenzenes. For instance, the reaction involves the alkylation/an addition of an alkyl group to an aromatic ring. Alongside, a catalyst (most commonly used is AlCl3) since it can act as a Lewis acid and generates an electrophile through the process of the reaction. Moreover, the Friedel-Crafts Alkylation reaction is recognized as an electrophilic aromatic substitution reaction. In other words, within the reaction a carbocation is attacked by a pi bond from an aromatic ring, resulting in the replacement of one of the aromatic protons by an alkyl group. All in all, the reaction process is widely utilized in numerous real world applications. For example, petroleum refining, medication modification in pharmacology, and pharmaceuticals. More importantly, alkylating drugs are utilized in treating multiple diseases, illnesses, and issues in the human body. For example, in the treatment of: brain tumo